导 师 简 介 | 个人简况：寇现娟，河南新乡人，教授，“东湖学子”，硕士研究生导师。华中科技大学同济医学院生物化学与分子生物学专业博士。目前，主要承担《系统解剖学》、《运动解剖学》、《老年病学》等课程的教学。 科研情况：主持国家自然科学基金项目、湖北省自然科学基金项目、湖北省教育厅人文社会科学研究项目、湖北省教育厅科学研究计划项目等课题10余项；参与国家自然基金项目、国家体育总局重点研究项目等省部级课题10项；发表文章30余篇；其中SCI、EI检索期刊20余篇；出版英文专著1部；多次参加奥运会科学报告会、亚运会科学报告会等国际学术会议，并做口头报告。 目前正致力于运动干预与脑衰老、肌萎缩、肿瘤等方面的研究。拟指导运动康复、康复治疗专业、运动医学等方向的研究生。 近年来发表的部分学术论文 [1] Xianjuan Kou , Biao Li , Julia B. Olayanju , Justin M. Drake and Ning Chen. Nutraceutical or Pharmacological Potential of Moringa oleifera Lam. Nutrients, 2018 10(3): pii: E343. （SCI收录） [2]Xianjuan Kou, Jingjing Fan, Ning Chen. Potential Molecular Targets of Ampelopsin in Prevention and Treatment of Cancers. Anticancer Agents Med Chem. 2017, 17(12):1610-1616. （SCI收录） [3] Xianjuan Kou, Jie Li, Xingran Liu, Xiaoqi Yang, Jingjing Fan, Ning Chen. Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/SIRT1/PGC-1α signaling cascade. Biomed Pharmacother. 2017, 90:311-320. （SCI收录） [4] Xianjuan Kou, Jie Li, Xingran Liu, Jingru Chang, Qingxia Zhao, Shaohui Jia, Jingjing Fan, Ning Chen. Swimming attenuates D-galactose-induced brain aging via suppressing miR-34a-mediated autophagy impairment and abnormal mitochondrial dynamics. J Appl Physiol (1985). 2017,122(6):1462-1469. （SCI收录） [5] Xianjuan Kou, Ning Chen. Resveratrol as a natural autophagy regulator for prevention and treatment of Alzheimer’s disease. Nutrients, 2017, 9(9): 927. （SCI收录） [6] Xianjuan Kou, Jie Li, Xingrang Liu, Jingjing Fan, Shaohui Jia, Ning chen. Ampelopsin attenuates brain aging of D-gal-induced rats through miR-34a-mediated SIRT1/mTOR signal pathway. Oncotarget, 2016,74484-74495. （SCI收录） [7] Jingjing Fan, Xianjuan Kou, Yi Yang, Ning Chen. MicroRNA-regulated proinflammatory cytokines in sarcopenia. Mediators of Inflammation, 2016, 2016: 1438686. (Co-first author). （SCI收录） [8] Xianjuan Kou, Jie Li, Jing Bian, Yi Yang, Xiaoqi Yang, Jingjing Fan, Shaohui Jia, Ning chen*. Ampelopsin attenuates 6-OHDA-induced neurotoxicity by regulating GSK-3β/NRF2/ARE signaling, Journal of Functional Foods, 2015,19: 765–774,. （SCI收录） [9] Xianjuan Kou, Keyin Shen, Yuhui An, Qi S, Wuxing Dai, Zhimin Yin. Ampelopsin Inhibits H2O2 -induced Apoptosis by ERK and Akt Signaling Pathways and Up-regulation of Heme Oxygenase-1, Phytother Research, 2012, 26: 988-994. （SCI收录） [10] Xianjuan Kou, Shimei Qi, Wuxing Dai, Lan Luo, Zhimin Yin. Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathway, International Immunopharmacol, 2011,11(8): 1095-102. （SCI收录） [11] Xianjuan Kou, Ning Chen, Zhiyong Feng, Zhimin Yin. GSTP1 Negatively Regulates Stat3 Activation in Epidermal Growth Factor Signaling, Oncology Letters, 2013, 5: 1053-1057. （SCI收录） [12] Xianjuan Kou, Ning Chen. Pharmacological Potential of Ampelopsin in Rattan Tea. Food Science and Human Wellness, 2012, 1:14-18. （英文核心） [13] Xianjuan Kou, Michael Kirberger, Yi Yang, Ning Chen. Natural Products for Cancer Prevention Associated withNrf2-ARE Pathway, Food Science and Human Wellness, 2013,1: 22-28. （英文核心） [14] Jing Bian, Bo Li, Xianjuan Kou, Tianzhou Liu, Liang Ming. Clinical significance of combined detection of serum tumor markers in diagnosis of patients with ovarian cancer. Asian pacific journal of cancer prevention, 2013, 6241-6243.（* corresponding autor）（SCI收录） [15] Shimei Qi, Xianjuan Kou, Jun Lv, Zhilin Qi, Liang Yan. Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways: Involvement of P38 and ERK, Environ Toxicol Pharmacol, 2015, 3:847-854. （SCI收录） [16]Jing Bian, Bo Li, Xianjuan Kou, Ming Liang. Clinical applicability of multi-tumor marker protein chips for diagnosing ovarian cancer. Aisan Pacific journal of Cancer Prevention, 2014,15(19):8409-8411. （SCI收录） |
